Defining Benchmarks for ALPPS - An Analysis of Low Risk Patients from the International ALPPS Registry

All currently registered patients in the International ALPPS registry will be initially included in a descriptive analysis focusing on data completion, basic demographics, indication for surgery, perioperative course, including completion of ALPPS step 2, postoperative morbidity, and 1-year survival. Then benchmark values will derive from a separate subgroup analysis on data from centers having included at least 30 patients in the ALPPS registry, patients younger than 67 years of age, and patients with colorectal metastasis alone. Benchmark values will be determined based on 7 parameters; completion of ALPPS step 2, complications of any severity, minor and major complications, the CCI, liver failure, and mortality up to 90 days, as well as the risk adjusted 1-year survival.